当前位置：
X-MOL 学术
›
J. Nat. Prod.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
(−)-trans-Δ9-Tetrahydrocannabiphorol Content of Cannabis sativa Inflorescence from Various Chemotypes
Journal of Natural Products ( IF 3.3 ) Pub Date : 2021-02-10 , DOI: 10.1021/acs.jnatprod.0c01034 Justin Bueno 1 , Eric A Greenbaum 1
Journal of Natural Products ( IF 3.3 ) Pub Date : 2021-02-10 , DOI: 10.1021/acs.jnatprod.0c01034 Justin Bueno 1 , Eric A Greenbaum 1
Affiliation
|
The (−)-trans-Δ9-tetrahydrocannabiphorol (Δ9-THCP, 1) content of the inflorescence from six Cannabis sativa chemotypes, including 14 plants of distinct genotypes, and two extracts was determined quantitatively via high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). This represents the first comprehensive quantitative screening for 1 from various C. sativa chemotypes. Compound 1 was detected in all 13 inflorescence samples originating from “(−)-trans-Δ9-tetrahydrocannabinol (Δ9-THC, 2) dominant” C. sativa chemotypes, but was not detected in a “cannabidiol (CBD, 3) dominant” chemotype. The inflorescence content of 1 ranged approximately from 0.0023% to 0.0136% (w/w). Comprehensive inflorescence sampling was performed for each specimen investigated. A trend between inflorescence cannabinoid potency and the location of which the inflorescence was sampled on the C. sativa plant was observed for the three cannabinoids tested (1–3). The preliminary results obtained indicate Δ9-THCP (1) may have a higher degree of prevalence in C. sativa inflorescence than previously estimated.
中文翻译：
来自不同化学型的大麻花序的 (-)-trans-Δ9-四氢大麻酚含量
六种大麻化学型（包括不同基因型的 14 株植物和两种提取物）的花序(-)-反式-Δ 9 -四氢大麻酚 (Δ 9 -THCP, 1 ) 含量通过高效液相色谱-串联进行定量测定质谱 (HPLC-MS/MS)。这是对来自不同C. sativa化学型的1的首次全面定量筛选。在源自“(-)-反式-Δ 9 -四氢大麻酚（Δ 9 -THC, 2）显性”的所有13个花序样品中均检测到化合物1C. sativa化学型，但未在“大麻二酚（CBD，3）显性”化学型中检测到。的花序内容1范围约从0.0023％至0.0136％（重量/重量）。对每个研究的标本进行全面的花序取样。花序大麻素效力并且其花序对所采样的位置之间的趋势C.苜蓿观察到（测试的三种植物大麻素1 - 3）。获得的初步结果表明 Δ 9 -THCP ( 1 ) 在C. sativa花序中的流行程度可能比先前估计的更高。
更新日期：2021-02-26
中文翻译：
来自不同化学型的大麻花序的 (-)-trans-Δ9-四氢大麻酚含量
六种大麻化学型（包括不同基因型的 14 株植物和两种提取物）的花序(-)-反式-Δ 9 -四氢大麻酚 (Δ 9 -THCP, 1 ) 含量通过高效液相色谱-串联进行定量测定质谱 (HPLC-MS/MS)。这是对来自不同C. sativa化学型的1的首次全面定量筛选。在源自“(-)-反式-Δ 9 -四氢大麻酚（Δ 9 -THC, 2）显性”的所有13个花序样品中均检测到化合物1C. sativa化学型，但未在“大麻二酚（CBD，3）显性”化学型中检测到。的花序内容1范围约从0.0023％至0.0136％（重量/重量）。对每个研究的标本进行全面的花序取样。花序大麻素效力并且其花序对所采样的位置之间的趋势C.苜蓿观察到（测试的三种植物大麻素1 - 3）。获得的初步结果表明 Δ 9 -THCP ( 1 ) 在C. sativa花序中的流行程度可能比先前估计的更高。
京公网安备 11010802027423号