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Comparison of Blood and Tissue Eosinophil Count and Blood IgE in Patients with Chronic Sinusitis and Nasal Polyps
Journal of Immunology Research ( IF 3.5 ) Pub Date : 2021-02-10 , DOI: 10.1155/2021/6680676
Masoud Asghari 1 , Shadi Izadpanahi 2 , Mina Heidari Esfahani 3
Affiliation  

Background. The inflammatory mucosa of the sinus cavities is called sinusitis and is divided into various types based on its appearance and sign. Chronic rhinosinusitis is an inflammatory-infectious disease that involves the frontal, sphenoid, ethmoid, and maxillary sinuses. Chronic sinusitis is a multifactorial disease and the range of causes varies from environmental factors to genetic factors. The purpose of this study was to compare blood and tissue eosinophils and serum IgE levels in patients with chronic sinusitis with nasal polyp in Vali-e-Asr hospital in 1397. Methods. In this descriptive-analytical study, the population under study included those with chronic sinusitis referred to Birjand Valiasr Hospital in 1397.3 cc of blood samples were taken 1 day before surgery to evaluate eosinophil counts and serum IgE levels. Also, samples taken from patients during surgery were counted, and then, 100 cells were counted, and eosinophil counts and percentages were calculated. The data were entered into the SPSS software after data collection. Results. This study was performed on 70 patients with chronic rhinosinusitis which included 43 men (61.4%) and 27 women (38.6%) with mean age of years. There was no significant difference between sex of patients and mean serum IgE level (). The mean percentage of eosinophils in blood samples and tissues of patients with chronic sinusitis was significantly increased with the increase in CT scan (). Conclusions. Tissue or blood eosinophilia was not observed in patients with chronic rhinosinusitis. Also, the mean eosinophil percentage of blood and tissue increased significantly in patients with increased scanning computed tomography ().

中文翻译:

慢性鼻窦炎和鼻息肉患者血液和组织嗜酸性粒细胞计数和血液 IgE 的比较

背景。鼻窦腔的炎症性黏膜称为鼻窦炎,根据其外观和体征分为多种类型。慢性鼻窦炎是一种炎症感染性疾病,累及额窦、蝶窦、筛窦和上颌窦。慢性鼻窦炎是一种多因素疾病,病因范围从环境因素到遗传因素不等。本研究的目的是比较 1397 年 Vali-e-Asr 医院慢性鼻窦炎合并鼻息肉患者的血液和组织嗜酸性粒细胞及血清 IgE 水平. 在这项描述性分析研究中,研究的人群包括那些被转诊到 Birjand Valiasr 医院的慢性鼻窦炎患者,在手术前 1 天采集了 1397.3 cc 的血样,以评估嗜酸性粒细胞计数和血清 IgE 水平。此外,对手术期间取自患者的样本进行计数,然后计数 100 个细胞,并计算嗜酸性粒细胞计数和百分比。数据采集​​后输入SPSS软件。结果。这项研究对 70 名慢性鼻窦炎患者进行,其中包括 43 名男性 (61.4%) 和 27 名女性 (38.6%),平均年龄为年。患者性别与平均血清 IgE 水平无显着差异()。慢性鼻窦炎患者血液样本和组织中嗜酸性粒细胞的平均百分比随 CT 扫描的增加而显着增加。)。 结论。在慢性鼻窦炎患者中未观察到组织或血液嗜酸性粒细胞增多。此外,扫描计算机断层扫描增加的患者血液和组织的平均嗜酸性粒细胞百分比显着增加。)。
更新日期:2021-02-10
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