Photoacoustic (PA) imaging provides morphological and functional information about angiogenesis and thus is potentially suitable for breast cancer diagnosis. However, the development of PA breast imaging has been hindered by inadequate patients and a lack of ground truth images. Here, we report a digital breast phantom with realistic acoustic and optical properties, with which a digital PA-ultrasound imaging pipeline is developed to create a diverse pool of virtual patients with three types of masses: ductal carcinoma in situ, invasive breast cancer, and fibroadenoma. The experimental results demonstrate that our model is realistic, flexible, and can be potentially useful for accelerating the development of PA breast imaging technology.

中文翻译：

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用于光声计算机断层扫描的数字化乳房幻影的开发

光声（PA）成像提供有关血管生成的形态学和功能信息，因此可能适合乳腺癌的诊断。但是，由于患者不足和缺乏地面实况图像，阻碍了PA乳房成像的发展。在这里，我们报告了一种具有逼真的声学和光学特性的数字化人体模型，并开发了一种数字化PA超声成像管道，以创建具有三种类型肿块的虚拟患者的多样化集合：原位导管癌，浸润性乳腺癌和纤维腺瘤。实验结果表明，我们的模型是现实的，灵活的，并且对于加速PA乳房成像技术的发展可能具有潜在的用处。