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Carbon-based nanomaterials for targeted cancer nanotherapy: recent trends and future prospects
Journal of Drug Targeting ( IF 4.3 ) Pub Date : 2021-02-18 , DOI: 10.1080/1061186x.2021.1886301
Mohaddeseh Sajjadi 1 , Mahmoud Nasrollahzadeh 1 , Babak Jaleh 2 , Ghazaleh Jamalipour Soufi 3 , Siavash Iravani 4
Affiliation  

Abstract

Carbon-based nanomaterials are becoming attractive materials due to their unique structural dimensions and promising mechanical, electrical, thermal, optical and chemical characteristics. Carbon nanotubes, graphene, graphene oxide, carbon and graphene quantum dots have numerous applications in diverse areas, including biosensing, drug/gene delivery, tissue engineering, imaging, regenerative medicine, diagnosis, and cancer therapy. Cancer remains one of the major health problems all over the world, and several therapeutic approaches are focussed on designing targeted anticancer drug delivery nanosystems by applying benign and less hazardous resources with high biocompatibility, ease of functionalization, remarkable targeted therapy issues, and low adverse effects. This review highlights the recent development on these carbon based-nanomaterials in the field of targeted cancer therapy and discusses their possible and promising diagnostic and therapeutic applications for the treatment of cancers.



中文翻译:

用于靶向癌症纳米治疗的碳基纳米材料:近期趋势和未来前景

摘要

碳基纳米材料因其独特的结构尺寸和良好的机械、电学、热学、光学和化学特性而成为有吸引力的材料。碳纳米管、石墨烯、氧化石墨烯、碳和石墨烯量子点在生物传感、药物/基因传递、组织工程、成像、再生医学、诊断和癌症治疗等不同领域有许多应用。癌症仍然是世界范围内的主要健康问题之一,几种治疗方法专注于设计靶向抗癌药物递送纳米系统,通过应用具有高生物相容性、易于功能化、显着靶向治疗问题和低副作用的良性和危害较小的资源.

更新日期:2021-02-18
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