Abstract

Sugarcane yeast and brewer’s yeast from ethanol production are widely used as ingredients of animal feed formulations in Brazil. To avoid the contamination of the must in ethanol production refineries, the use of antibiotics is one of the main preventive treatments. Thus, there is a risk of antibiotic residues carry over from yeast to animal feed. This unintentional addition of antibiotics can produce non-compliant feed products, due to regulatory aspects and their toxicity for animals. The results of an exploratory program to assess the occurrence of over 60 antibiotics and other pharmaceuticals in 27 sugarcane yeast and brewer’s yeast samples were described. Monensin was present in seven samples with concentrations ranging from 0.47 to 263.5 mg kg⁻¹. Other antibiotics quantitated were virginiamycin (2.25 mg kg⁻¹) and amprolium (0.25 mg kg⁻¹). Monensin in sugarcane yeast may represent a risk for further feeds production, especially for those products intended for sensible species such as equines and rabbits, for which monensin has toxic effects.

摘要

来自乙醇生产的甘蔗酵母和啤酒酵母广泛用作巴西动物饲料配方的成分。为了避免乙醇生产精炼厂的芥末污染，抗生素的使用是主要的预防方法之一。因此，存在抗生素残留物从酵母转移到动物饲料的风险。由于监管方面及其对动物的毒性，无意中添加抗生素会产生不合格的饲料产品。描述了评估27种甘蔗酵母和啤酒酵母样品中60多种抗生素和其他药物的存在的探索性计划的结果。莫能菌素存在于七个样品中，浓度范围为0.47至263.5 mg kg ^-1。定量的其他抗生素是维吉尼亚霉素（2.25 mg kg ^-1）和氨苯丙胺（0.25 mg kg ^-1）。甘蔗酵母中的莫能菌素可能代表进一步饲料生产的风险，尤其是对于那些对莫能菌素具有毒性作用的敏感物种（如马和兔子）而言。