Resveratrol (RES) is a plant extract with excellent antioxidant, biocompatibility, anti-inflammatory and inhibition of platelet aggregation. RES-modified polysulfone (PSF) hemodialysis membranes have been fabricated using an immersion phase transformation method. The antioxidant properties of the blend membranes were evaluated in terms of their 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS⁺), reactive oxygen species (ROS) free radicals scavenging, total antioxidant capacity (T-AOC) of serum and lipid peroxidation inhibition. The observed results of decreasing DPPH and ABTS⁺ levels, scavenging ROS, significant inhibition of lipid peroxidation and improving the T-AOC of serum all contribute to the recovery of oxidative balance and the use of RES as an antioxidant modifier. The antioxidant stability of PSF/RES blend membranes was also studied. Moreover, the results of blood compatibility experiments showed that the addition of RES improved the blood compatibility of PSF membrane, inhibited the adhesion of red blood cells and platelets; inhibited complement activation; and reduced the blood cells deformation rate. The dialysis simulation experiment indicated that PSF/RES membrane (M-3) can clear 90.33% urea, 89.50% creatinine, 74.60% lysozyme and retention 90.47% BSA. All these results showed the new PSF/RES blend membranes have potential to be used in the field of hemodialysis to improve oxidative stress status in patients.

白藜芦醇（RES）是一种植物提取物，具有出色的抗氧化剂，生物相容性，抗炎性和抑制血小板聚集的作用。RES改性聚砜（PSF）血液透析膜已使用浸没相变法制备。根据它们的2,2-二苯基-1-吡啶并肼基（DPPH）和2,2'-叠氮基双-（3-乙基苯并噻唑啉-6-磺酸盐）（ABTS ⁺），活性氧来评估共混膜的抗氧化性能（ROS）清除自由基，血清总抗氧化能力（T-AOC）和脂质过氧化抑制作用。降低DPPH和ABTS ⁺的观察结果水平，清除ROS，显着抑制脂质过氧化和改善血清的T-AOC均有助于恢复氧化平衡，以及使用RES作为抗氧化剂。还研究了PSF / RES共混膜的抗氧化稳定性。此外，血液相容性实验结果表明，加入RES改善了PSF膜的血液相容性，抑制了红细胞和血小板的粘附。抑制补体激活；并降低了血细胞变形率。透析模拟实验表明，PSF / RES膜（M-3）可以清除90.33％的尿素，89.50％的肌酸酐，74.60％的溶菌酶和90.47％的BSA。