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Dexmedetomidine attenuates lipopolysaccharide induced acute liver injury in rats by inhibiting caveolin-1 downstream signaling pathway.
Bioscience Reports ( IF 3.8 ) Pub Date : 2021-02-09 , DOI: 10.1042/bsr20204279
Fei Tong 1 , Wenchao Shen 2 , Pengtao Song 3 , Jiafeng Song 3 , Yonghe Hu 1 , Feifan Liu 1 , Zhipeng Meng 1 , Jing Liu 4
Affiliation  

The aim of this study is to investigate the anti-injury and anti-inflammatory effects of dexmedetomidine(Dex) in acute liver injury induced by lipopolysaccharide(LPS) in Sprague-Dawley rats and its possible mechanism.

中文翻译:

右美托咪定通过抑制caveolin-1下游信号通路减轻脂多糖诱导的大鼠急性肝损伤。

本研究旨在探讨右美托咪定(Dex)对脂多糖(LPS)致Sprague-Dawley大鼠急性肝损伤的抗损伤、抗炎作用及其可能机制。
更新日期:2021-02-11
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