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Carboxyl fuchsine-based colored particles for application to immunodetection
International Journal of Polymeric Materials and Polymeric Biomaterials ( IF 2.5 ) Pub Date : 2021-02-08 , DOI: 10.1080/00914037.2021.1876056
A. Lis Femia 1 , Verónica D. G. Gonzalez 1, 2 , Valeria S. Garcia 1 , Luis M. Gugliotta 1, 3
Affiliation  

Abstract

Functionalized latex particles (FLP) are normally applied for diagnosis and therapeutics purposes and, in particular, the interest in colored FLP is rising in areas such as biomedical and research. The synthesis, characterization and application of FLP with a new colored monomer is here considered, in a simple and fast manner, and at low cost. Synthesis variables were controlled to obtain particles of different size, surface charge and color incorporation. Then, particles were proved in protein binding assays; and the development of an immunochromatographic test was successfully performed.



中文翻译:

用于免疫检测的羧基品红基着色颗粒

摘要

功能化乳胶颗粒 (FLP) 通常用于诊断和治疗目的,特别是在生物医学和研究等领域,对彩色 FLP 的兴趣正在上升。本文以简单、快速、低成本的方式考虑了具有新的有色单体的 FLP 的合成、表征和应用。控制合成变量以获得不同尺寸、表面电荷和颜色结合的颗粒。然后,在蛋白质结合试验中证明了颗粒;并成功进行了免疫层析试验的开发。

更新日期:2021-02-08
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