Using Fluorescence to Enable Innovative Functions of Foldamers,Israel Journal of Chemistry

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Using Fluorescence to Enable Innovative Functions of Foldamers
Israel Journal of Chemistry ( IF 2.3 ) Pub Date : 2021-02-09 , DOI: 10.1002/ijch.202000109
Amelia A. Fuller ₁ , Jose L. Moreno ₁ , Michelle T. Nguyen ₁

Affiliation

Monodisperse, sequence‐specific oligomers that adopt regular three‐dimensional structures, termed foldamers, have found widespread use as biomimetics, sensors, and novel materials. This review highlights recent examples in which steady state and time‐resolved fluorescence techniques have clarified foldamer structure or enabled the development of foldamers with exciting and sophisticated functions. Applications of foldamers include their development into bioactive compounds, supramolecular hosts or sensors, and materials with useful optical properties. Examples that illustrate the use of natively fluorescent and fluorophore‐modified foldamers are discussed along with studies of fluorophore interactions with varied dyes.

中文翻译：

使用荧光来实现Foldamers的创新功能

具有规则三维结构的单分散，序列特定的低聚物，称为折叠剂，已被广泛用作仿生物，传感器和新型材料。这篇综述重点介绍了最近的例子，这些例子中的稳态和时间分辨荧光技术已经阐明了折叠器的结构或使折叠器的开发具有令人兴奋和复杂的功能。折叠剂的应用包括将其开发为生物活性化合物，超分子主体或传感器以及具有有用光学性质的材料。讨论了使用天然荧光和荧光团修饰的折叠剂的实例，并研究了荧光团与各种染料的相互作用。

更新日期：2021-02-09

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