Type 1 innate lymphoid cells (ILC1s) regulate inflammation in the tissues; however, their role in anti-viral immunity remains largely unknown. In this issue of Immunity, Shannon et al. report that ILC1s invoke an anti-viral effect by producing interferon (IFN)γ at homeostasis, thereby limiting viral replication in the oral mucosa.

中文翻译：

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ILC1：口腔粘膜抵御敌方病毒的卫士

1 型先天淋巴细胞 (ILC1) 调节组织炎症；然而，它们在抗病毒免疫中的作用仍然很大程度上未知。在本期《免疫》中，香农等人。报道称，ILC1 通过在稳态时产生干扰素 (IFN)γ 来激发抗病毒作用，从而限制口腔粘膜中的病毒复制。