The objectives of this study were to evaluate the effects of different salinity levels on tissue histology, blood biochemistry, and genes transcription of the GH/IGF system in juvenile golden trout (Oncorhynchus mykiss). Five experimental salinity levels (0, 8, 16, 24, and 32‰) were selected to domesticate juvenile O. mykiss for 7 days. Histological characteristics changed with salinity, including higher ionocites area and epithelium thickness in gills, narrow lumen of collecting tubules in kidneys, and high numbers of goblet cells in the intestines. Similarly, increments in slits, degenerate hepatocytes, and individualization of hepatocytes have been shown in fish reared in the 32‰ salinity group. The lowest triglyceride (TG) and the highest level of total protein (TP) were detected in fish reared at the 32‰ group. The genes transcription of the GH/IGF system altered in response to the increase of salinity. The present results add to the understanding of the physiological responses of O. mykiss on salinity stress and would be helpful in formulating strategies to optimize the aquaculture of this species in environments with fluctuating patterns of salinity.

这项研究的目的是评估不同盐度对少年鳟鱼（Oncorhynchus mykiss）的组织组织学，血液生化和GH / IGF系统基因转录的影响。选择了五个实验盐度水平（0、8、16、24和32‰）来驯化幼年O. mykiss7天。组织学特征随盐度的变化而变化，包括较高的电离卵石面积和g的上皮厚度，肾脏中收集小管的狭窄内腔以及肠中的杯状细胞数量高。同样，在32‰盐度组中饲养的鱼中，已经显示出裂隙的增加，变性的肝细胞和肝细胞的个体化。在32‰组饲养的鱼中，最低甘油三酸酯（TG）和最高总蛋白（TP）。GH / IGF系统的基因转录响应盐度的增加而改变。目前的结果增加了对O. mykiss的生理反应的理解。 盐度胁迫，将有助于制定策略，在盐度波动的环境中优化该物种的水产养殖。