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SINE-B1 Distribution and Chromosome Rearrangements in the South American Proechimys gr. goeldii (Echimyidae, Rodentia)
Cytogenetic and Genome Research ( IF 1.7 ) Pub Date : 2021-02-08 , DOI: 10.1159/000513106
Naiara P. Araújo , Radarane S. Sena , Cibele R. Bonvicino , Gustavo C.S. Kuhn , Marta Svartman

Proechimys species are remarkable for their extensive chromosome rearrangements, representing a good model to understand genome evolution. Herein, we cytogenetically analyzed 3 different cytotypes of Proechimys gr. goeldii to assess their evolutionary relationship. We also mapped the transposable element SINE-B1 on the chromosomes of P. gr. goeldii in order to investigate its distribution among individuals and evaluate its possible contribution to karyotype remodeling in this species. SINE-B1 showed a dispersed distribution along chromosome arms and was also detected at the pericentromeric regions of some chromosomes, including pair 1 and the sex chromosomes, which are involved in chromosome rearrangements. In addition, we describe a new cytotype for P. gr. goeldii, reinforcing the significant role of gross chromosomal rearrangements during the evolution of the genus. The results of FISH with SINE-B1 suggest that this issue should be more deeply investigated for a better understanding of its role in the mechanisms involved in the wide variety of Proechimys karyotypes.
Cytogenet Genome Res


中文翻译:

南美Proechimys gr。中的SINE-B1分布和染色体重排 goeldii(E科,啮齿类)

原虫属物种因其广泛的染色体重排而著称,是理解基因组进化的良好模型。在本文中,我们在细胞遗传学上分析了Proechimys gr的3种不同细胞类型goeldii评估其进化关系。我们还绘制了转座因子SINE-B1在P. gr的染色体上。戈尔德伊为了研究其在个体中的分布并评估其对该物种核型重塑的可能贡献。SINE-B1沿着染色体臂显示出分散的分布,并且在某些染色体的着丝粒区域也被检测到,包括第1对和性染色体,这些染色体与染色体重排有关。此外,我们描述了一种新的P. gr细胞类型。goeldii,增强了总染色体重排在属进化过程中的重要作用。带有SINE-B1的FISH结果表明,应该对该问题进行更深入的研究,以更好地了解其在多种原核生物核型中所涉及机制中的作用。
细胞遗传基因组研究
更新日期:2021-02-08
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