Graphene research has become an emerging frontier in materials science because of its potential as a versatile material in multiple applications, from electronics, sensors, water treatment, batteries, displays, advanced composites, and coatings to biomedical applications. While the community has witnessed tremendous advances in the laboratory-scale synthesis of graphene, it is crucial to focus on sustainable large-scale graphene production to adopt graphene-based technology at an industrial scale. Several top-down and bottom-up methods have been developed to realize affordable graphene production. However, a low-cost scalable graphene production method with acceptable quality remains a challenge; top-down processes are demonstrating their potential to offer a more straightforward solution. Herein, we present an overview of recent progress in the research and development of top-down graphene synthesis methods and their potential to scale-up graphene production. We cover the effect of different synthesis parameters on the quality control of graphene. In addition, we provide a brief overview of bottom-up methods. Finally, we discuss the existing challenges and future directions in top-down methods for large-scale graphene production.

石墨烯研究已成为材料科学领域的新兴前沿，因为它在电子，传感器，水处理，电池，显示器，高级复合材料，涂料和生物医学应用等多种应用中具有通用性，具有潜力。尽管社区见证了石墨烯实验室规模合成的巨大进步，但关键是要专注于可持续大规模石墨烯生产，以工业规模采用基于石墨烯的技术。已经开发了几种自上而下和自下而上的方法以实现可负担的石墨烯生产。然而，一种具有可接受质量的低成本可扩展石墨烯生产方法仍然是一个挑战。自上而下的过程表明了其提供更直接解决方案的潜力。在此处，我们概述了自上而下的石墨烯合成方法的研究和开发的最新进展及其在扩大石墨烯生产中的潜力。我们涵盖了不同合成参数对石墨烯质量控制的影响。此外，我们对自下而上的方法进行了简要概述。最后，我们讨论了自顶向下方法用于大规模石墨烯生产的现有挑战和未来方向。