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A Malignant Case of Arrested Development: Cancer Cell Dormancy Mimics Embryonic Diapause
Cancer Cell ( IF 48.8 ) Pub Date : 2021-02-08 , DOI: 10.1016/j.ccell.2021.01.013
Yu-Hsuan Lin 1 , Hao Zhu 1
Affiliation  

Writing in Cancer Cell and Cell, two groups investigate the nature of dormant cancer cells that persist after chemotherapy. These cells adopt a state that resembles diapause, an evolutionarily conserved adaptation used by embryos to survive inhospitable conditions. Understanding cancer diapause could uncover therapeutic strategies that reduce cancer relapse.



中文翻译:

发育受阻的恶性病例:癌细胞休眠模拟胚胎滞育

Cancer CellCell 中写作,两组研究化疗后持续存在的休眠癌细胞的性质。这些细胞采用类似于滞育的状态,这是胚胎用来在恶劣条件下生存的进化上保守的适应。了解癌症滞育可以发现减少癌症复发的治疗策略。

更新日期:2021-02-08
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