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Heterogeneity in Metastatic Potential of Cancer Cells Is Revealed En Masse
Cancer Cell ( IF 48.8 ) Pub Date : 2021-02-08 , DOI: 10.1016/j.ccell.2021.01.017 Pavitra Viswanath 1 , Alana L Welm 1
中文翻译:
大量揭示癌细胞转移潜能的异质性
更新日期:2021-02-08
Cancer Cell ( IF 48.8 ) Pub Date : 2021-02-08 , DOI: 10.1016/j.ccell.2021.01.017 Pavitra Viswanath 1 , Alana L Welm 1
Affiliation
A new study in Nature determines metastatic tropism in xenograft mouse models. This results in a metastasis map for 21 tumor types, the utility of which is demonstrated by identifying lipid metabolism to be uniquely altered in breast cancer cell lines that metastasize to the brain.
中文翻译:
大量揭示癌细胞转移潜能的异质性
Nature 上的一项新研究确定了异种移植小鼠模型的转移性。这产生了 21 种肿瘤类型的转移图,其效用通过确定在转移到大脑的乳腺癌细胞系中发生独特改变的脂质代谢来证明。