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Polarization multi-parametric imaging method for the inspection of cervix cell
Optics Communications ( IF 2.2 ) Pub Date : 2021-02-06 , DOI: 10.1016/j.optcom.2021.126846
Weiping Liu , Jichuan Xiong , Juan Liu , Jing Zhu , Jinlian Hu , Lianping Hou , John H. Marsh , Muhua Yi , Xuefeng Liu

Accurate identification of the shape and texture properties of cervical cell nuclei and cytoplasm in the pap smear test is crucial for the diagnosis of cervical cancer. Fast and high-precision polarization modulation in the Polarization Indirect Microscopic Imaging (PIMI) is achieved by utilizing a liquid crystal polarization rotator. Imaging results of cervical cells show that the PIMI method can resolve detailed fine structural features of a cervical cell which are invisible in conventional microscopy. It also demonstrated the ability of embossed three-dimensional visualization as that in differential interference contrast microscopy (DIC), but with finer structural features.



中文翻译:

偏振多参数成像法检查宫颈细胞

在子宫颈抹片检查中准确识别宫颈细胞核和细胞质的形状和质地特性对于宫颈癌的诊断至关重要。通过利用液晶偏振旋转器,可以实现偏振间接显微镜成像(PIMI)中的快速和高精度偏振调制。子宫颈细胞的成像结果表明,PIMI方法可以解决子宫颈细胞的详细精细结构特征,而这些特征在常规显微镜下是不可见的。它也展示了压花三维可视化的能力,如微分干涉对比显微镜(DIC)一样,但具有更精细的结构特征。

更新日期:2021-02-15
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