The development of multimodal nanoprobes has been growing in recent years. Among these novel nanostructures are bimodal systems based on quantum dots (QDs) and low molecular weight Gd³⁺ chelates, prepared for magnetic resonance imaging (MRI) and optical analyses. MRI is a technique used worldwide that provides anatomic resolution and allows distinguishing of physiological differences at tissue and organ level. On the other hand, optical techniques are very sensitive and allow events to be followed at the cellular or molecular level. Thus, the association of these two techniques has the potential to achieve a more complete comprehension of biological processes. In this review, we present state-of-the-art research concerning the development of potential multimodal optical/paramagnetic nanoprobes based on Gd³⁺ chelates and QDs, highlighting their preparation strategies and overall properties.

近年来，多峰纳米探针的发展一直在增长。在这些新颖的纳米结构中，包括基于量子点（QD）和低分子量Gd ³⁺螯合物的双峰系统，这些系统为磁共振成像（MRI）和光学分析而准备。MRI是一种在世界范围内使用的技术，可提供解剖学分辨率并允许在组织和器官水平上区分生理差异。另一方面，光学技术非常敏感，并允许在细胞或分子水平上跟踪事件。因此，这两种技术的结合具有实现对生物过程更完整理解的潜力。在这篇综述中，我们介绍了有关基于Gd的潜在多峰光学/顺磁纳米探针开发的最新研究。^{3种以上的}螯合物和QD，突出了它们的制备策略和整体性能。