The short stability window of several hours from blood collection to measuring basophil activation has limited the use of flow cytometry-based basophil activation assays in clinical settings. We examine if it is possible to extend this window to 1 day allowing for shipment of samples between laboratories. Several options exist for reporting the results including reporting all the measured values directly, calculating ratios and reporting a single value covering all measured results. Each of these options have different stability and value to the physician.

中文翻译：

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可诱导嗜碱性粒细胞生物标志物的验证：时间、温度和运输

从采血到测量嗜碱性粒细胞活化几个小时的短暂稳定性窗口限制了基于流式细胞术的嗜碱性粒细胞活化测定在临床环境中的使用。我们检查是否可以将此窗口延长至 1 天，以便在实验室之间运送样品。存在多种报告结果的选项，包括直接报告所有测量值、计算比率和报告涵盖所有测量结果的单个值。这些选项中的每一个对医生都有不同的稳定性和价值。