This article provides an update on the global cancer burden using the GLOBOCAN 2020 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer. Worldwide, an estimated 19.3 million new cancer cases (18.1 million excluding nonmelanoma skin cancer) and almost 10.0 million cancer deaths (9.9 million excluding nonmelanoma skin cancer) occurred in 2020. Female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer, with an estimated 2.3 million new cases (11.7%), followed by lung (11.4%), colorectal (10.0 %), prostate (7.3%), and stomach (5.6%) cancers. Lung cancer remained the leading cause of cancer death, with an estimated 1.8 million deaths (18%), followed by colorectal (9.4%), liver (8.3%), stomach (7.7%), and female breast (6.9%) cancers. Overall incidence was from 2‐fold to 3‐fold higher in transitioned versus transitioning countries for both sexes, whereas mortality varied <2‐fold for men and little for women. Death rates for female breast and cervical cancers, however, were considerably higher in transitioning versus transitioned countries (15.0 vs 12.8 per 100,000 and 12.4 vs 5.2 per 100,000, respectively). The global cancer burden is expected to be 28.4 million cases in 2040, a 47% rise from 2020, with a larger increase in transitioning (64% to 95%) versus transitioned (32% to 56%) countries due to demographic changes, although this may be further exacerbated by increasing risk factors associated with globalization and a growing economy. Efforts to build a sustainable infrastructure for the dissemination of cancer prevention measures and provision of cancer care in transitioning countries is critical for global cancer control.

中文翻译：

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2020 年全球癌症统计数据：GLOBOCAN 对 185 个国家/地区 36 种癌症的全球发病率和死亡率估计

本文使用国际癌症研究机构编制的 GLOBOCAN 2020 对癌症发病率和死亡率的估计提供了有关全球癌症负担的最新信息。据估计，2020 年全球发生了 1930 万新癌症病例（1810 万，不包括非黑色素瘤皮肤癌）和近 1000 万癌症死亡病例（不包括非黑色素瘤皮肤癌 990 万）。女性乳腺癌已超过肺癌成为最常被诊断出的癌症，其中估计有 230 万新病例 (11.7%)，其次是肺癌 (11.4%)、结直肠癌 (10.0%)、前列腺癌 (7.3%) 和胃癌 (5.6%)。肺癌仍然是癌症死亡的主要原因，估计有 180 万人死亡 (18%)，其次是结直肠癌 (9.4%)、肝癌 (8.3%)、胃癌 (7.7%) 和女性乳腺癌 (6.9%)。与转型国家相比，转型国家男女的总体发病率高出 2 到 3 倍，而男性的死亡率变化小于 2 倍，女性的死亡率变化很小。然而，女性乳腺癌和宫颈癌的死亡率在转型国家与转型国家相比要高得多（分别为每 100,000 人 15.0 vs 12.8 和每 100,000 人 12.4 vs 5.2）。预计 2040 年全球癌症负担将达到 2840 万例，比 2020 年增加 47%，由于人口变化，转型国家（64% 至 95%）与转型国家（32% 至 56%）相比增幅更大，尽管与全球化和经济增长相关的风险因素增加，可能会进一步加剧这种情况。