Objective

To develop an item response theory (IRT)-calibrated patient-reported outcome measure (the PROMIS® Cancer Function Brief 3D Profile) of physical function, including associations with fatigue and social participation, in cancer rehabilitation patients.

Design

Large-scale field-testing, graded response model IRT analyses, and multivariate regression analysis.

Setting

Six cancer rehabilitation clinics associated with cancer centers across the United States.

Participants

Adults treated in outpatient cancer rehabilitation medicine clinics.

Intervention

n/a

Results

616 patients completed 21 items in the initial item pool. Nine items were removed because of comparatively lower information that they provide according to the IRT item calibrations, low item-total correlations and/or bimodal distributions. The remaining items generated a twelve-item short form. Regression analyses determined that the items were responsive to and representative of the patient population across trait ranges and multiple domains/subdomains of function.

Conclusions

This psychometric investigation supports the use of the PROMIS® Cancer Function Brief 3D Profile for evaluating function in outpatient cancer rehabilitation patients.

中文翻译：

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PROMIS® Cancer Function Brief 3D Profile 的心理特征和有效性

客观的

开发一种项目反应理论 (IRT) 校准的患者报告结果测量（PROMIS® Cancer Function Brief 3D Profile），用于癌症康复患者的身体功能，包括与疲劳和社会参与的关联。

设计

大规模现场测试、分级响应模型 IRT 分析和多元回归分析。

环境

与美国癌症中心相关的六家癌症康复诊所。

参与者

在门诊癌症康复医学诊所接受治疗的成年人。

干涉

不适用

结果

616 名患者完成了初始项目库中的 21 个项目。九个项目被删除，因为它们根据 IRT 项目校准提供的信息相对较低、项目与总相关性低和/或双峰分布。其余项目生成了一个包含十二项的简短表格。回归分析确定这些项目对跨特征范围和多个功能域/子域的患者群体有反应并代表了患者群体。

结论

这项心理调查支持使用 PROMIS® Cancer Function Brief 3D Profile 来评估门诊癌症康复患者的功能。