Abstract

BACKGROUND:

Sedentarism is an important modifiable risk factor in the struggle against cancer. In the last decades, the relationship between physical activity and different types of cancer has been investigated in depth.

OBJECTIVE:

To provide an overview of the literature on the effectiveness of physical activity in reducing the risk to develop bladder cancer and improving health-related quality of life in patients.

METHODS:

A systematic review was conducted through a search of the Embase, Cochrane, PubMed, Scopus, and Web of Science (WOS) databases to seek information and PRISMA system to delimitate the research. Outcomes included in searches were physical activity, tobacco consumption, obesity, body mass index, and metabolic syndrome, associated with bladder cancer and quality of life.

RESULTS:

Database searches identified 394 records, of which 75 were duplicated. A total of 280 articles were excluded based on abstract screening. An additional 16 full-text articles were excluded because they did not meet the eligibility criteria. Overall, 21 of the 23 studies included in the review reported beneficial effects of physical activity in bladder cancer. The majority of papers found that physical activity is a significant factor in reducing the risk of bladder cancer. Moreover, physical activity improves health-related quality of life in bladder cancer survivors, and diminishes both recurrence and mortality in those who engage in regular activity. Lastly, physical inactivity is associated with increased body mass index, obesity, metabolic syndrome, type 2 diabetes and unfavourable energy balance, which led to a greater probability of suffering from bladder cancer.

CONCLUSIONS:

These data reinforce the importance of promoting a healthy lifestyle to reduce the risk of bladder cancer and to improve survivorship and health-related quality of life of patients.

中文翻译：

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系统评价：体力活动对膀胱癌风险和健康相关生活质量的影响

 抽象的

 背景：

久坐是抗击癌症的一个重要的可改变的危险因素。在过去的几十年中，人们对身体活动与不同类型癌症之间的关系进行了深入研究。

 客观的：

概述关于体力活动在降低患膀胱癌风险和改善患者健康相关生活质量方面的有效性的文献。

 方法：

通过检索 Embase、Cochrane、PubMed、Scopus 和 Web of Science (WOS) 数据库来寻找信息并使用 PRISMA 系统来界定研究，从而进行了系统评价。搜索结果包括与膀胱癌和生活质量相关的体力活动、烟草消费、肥胖、体重指数和代谢综合征。

 结果：

数据库搜索发现 394 条记录，其中 75 条重复。根据摘要筛选，总共排除了 280 篇文章。另外 16 篇全文文章因不符合资格标准而被排除。总体而言，该综述纳入的 23 项研究中有 21 项报告了体力活动对膀胱癌的有益影响。大多数论文发现体力活动是降低膀胱癌风险的重要因素。此外，体力活动可以改善膀胱癌幸存者的健康相关生活质量，并降低定期活动患者的复发率和死亡率。最后，身体活动不足与体重指数增加、肥胖、代谢综合征、2型糖尿病和不利的能量平衡有关，从而导致患膀胱癌的可能性更大。

 结论：

这些数据强调了促进健康生活方式以降低膀胱癌风险并提高患者生存率和健康相关生活质量的重要性。