This work investigates the quality of emulsions obtained from fast emulsification in a microsystem implemented at high throughput. The aim is to manufacture oil in water (O/W) emulsions in which bioactive ingredients could be encapsulated. These emulsions may be of interest for cosmetic, nutraceutical and/or pharmaceutical applications. A microsystem based on an improved cross-slot configuration is tested for production of emulsions with various formulations in a range of flow rate comprised in 100−600 mL/min. Dispersed lipid phase consists mainly in sunflower oil. The continuous aqueous phase is a Non-Newtonian fluid as it includes xanthan in order to stabilize the emulsions. Several commercial surfactants are also used to stabilize the emulsions. Their stability is examined during a storage period of approximately 30 days. For most tests, the evaluation of emulsions is based on a comparison with emulsions produced from a commercial laboratory rotor stator emulsifier. The results show only a few slight differences between the characteristics of emulsions generated in continuous in the microsystem and those obtained from the batch rotor-stator emulsifier. The results are therefore mostly comparable, which leads to the conclusion that microsystems can offer an interesting alternative to the small-scale production of emulsions.

这项工作研究了在高通量实施的微系统中从快速乳化获得的乳液的质量。目的是制造可以封装生物活性成分的水包油（O / W）乳液。这些乳液对于化妆品，营养保健品和/或药物应用可能是令人感兴趣的。测试了基于改进的十字槽构型的微系统，以100-600 mL / min的流量范围生产各种配方的乳液。分散脂质相主要包含葵花籽油。连续水相是非牛顿流体，因为它包含黄原胶以稳定乳液。几种市售的表面活性剂也用于稳定乳液。在大约30天的存储期内检查其稳定性。对于大多数测试，乳液的评估是基于与商用实验室转子定子乳化剂生产的乳液的比较。结果表明，在微系统中连续产生的乳液特性与从间歇转子-定子乳化剂获得的乳液特性之间仅有微小的差异。因此，结果几乎是可比较的，从而得出结论：微系统可以为小规模生产乳液提供有趣的替代方法。