In the absence of a vaccine, preventing the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the primary means to reduce the impact of the 2019 coronavirus disease (COVID-19). Multiple studies have reported the presence of SARS-CoV-2 genetic material on surfaces suggesting that fomite transmission of SARS-CoV-2 is feasible. High temperature inactivation of virus has been previously suggested, but not shown. In the present study, we investigated the environmental stability of SARS-CoV-2 in a clinically relevant matrix dried onto stainless steel at a high temperature. The results show that at 54.5 °C, the virus half-life was 10.8 ± 3.0 min and the time for a 90% decrease in infectivity was 35.4 ± 9.0 min. These findings suggest that in instances where the environment can reach temperatures of at least 54.5 °C, such as in vehicle interior cabins when parked in warmer ambient air, that the potential for exposure to infectious virus on surfaces could be decreased substantially in under an hour.

在没有疫苗的情况下，防止严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 的传播是减少 2019 年冠状病毒病 (COVID-19) 影响的主要手段。多项研究报告称，表面上存在 SARS-CoV-2 遗传物质，表明 SARS-CoV-2 的污染物传播是可行的。先前已提出病毒的高温灭活，但未显示。在本研究中，我们研究了 SARS-CoV-2 在高温下干燥到不锈钢上的临床相关基质中的环境稳定性。结果表明，在 54.5 °C 时，病毒半衰期为 10.8 ± 3.0 min，传染性下降 90% 的时间为 35.4 ± 9.0 min。这些发现表明，在环境温度可以达到至少 54.5 °C 的情况下，