This study aimed to investigate the effect of acute endurance exercise on cardiac and skeletal muscles in smokers and non-smokers. Eight daily smokers (28.44 ± 3.94 years) and nine non-smokers (29.62 ± 3.46 years) were included. The subjects were not trained and performed continuous endurance exercise on a treadmill for 40 minutes at 70% of maximal heart rate. Venous blood samples were collected at baseline [preexercise (PRE)], at immediately after the exercise [post-exercise (POST)], at 2 hours after the exercise (2h), at 24 hours after the exercise (24h) to measure lactate dehydrogenase (LDH), creatine kinase(CK), creatine kinase-myocardial band (CK-MB), cardiac troponin T (TN-T), and myoglobin levels. A progressive increase was observed in all exercise-induced muscle damage parameters of the smoker and non-smoker from PRE to 2h. CK, myoglobin and T-NT levels of smokers were significantly higher than non-smokers at 24h (p=0.039, p=0.018 p=0.008, respectively). No significant difference was found between the smoking and non-smoking groups at all time points regarding CK-MB and LDH levels (p>0.05). Acute endurance exercise leads to more skeletal and myocardial damage in smokers compared to non-smokers. Smoking may increase the risk of cardiovascular events during both exercise and daily physical activity.

中文翻译：

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抽烟检查运动引起的骨骼和心脏肌肉损伤

这项研究旨在调查急性耐力运动对吸烟者和非吸烟者心脏和骨骼肌的影响。包括八名每日吸烟者（28.44±3.94岁）和九名不吸烟者（29.62±3.46岁）。没有对受试者进行训练，并且在跑步机上以最大心率的70％进行了40分钟的连续耐力运动。在基线[运动前（PRE）]，运动后立即[运动后（POST）]，运动后2小时（2h），运动后24小时（24h）收集静脉血样本以测量乳酸脱氢酶（LDH），肌酸激酶（CK），肌酸激酶心肌带（CK-MB），心肌肌钙蛋白T（TN-T）和肌红蛋白水平。从PRE到2h，吸烟者和非吸烟者的运动引起的所有肌肉损伤参数均逐渐增加。CK，吸烟者24小时的肌红蛋白和T-NT水平显着高于非吸烟者（分别为p = 0.039，p = 0.018和p = 0.008）。在所有时间点，吸烟组和不吸烟组之间在CK-MB和LDH水平上均无显着差异（p> 0.05）。与非吸烟者相比，急性耐力运动对吸烟者的骨骼和心肌损伤更大。吸烟可能会增加运动和日常体育锻炼中发生心血管事件的风险。