Despite tremendous developments in synthetic medicine, medicinal plants are still commonly used for the management of diabetes mellitus. This study synthesized scientific evidence on commonly used medicinal plants for the management of diabetes mellitus (DM) in Ethiopia. Databases (PubMed, Cochrane, CINAHL and Google Scholar) have been thoroughly sought and evidence was synthesized. Thirty studies conducted anti-diabetic activities studies on 19 medicinal plants in Ethiopia. Most of the studies were in vivo studies (25). Others include; clinical study (1), in vitro studies (2), and both in vivo and in vitro study (2). Trigonella foenum-graecum L., clinical study, showed an improved lipid profile in type II diabetic patients. Comparable blood sugar level (BSL) lowering effect to glibenclimide was observed with Persea Americana and Moringa stenopetala. Noteworthy in vitro half maximal inhibitory concentration (IC 50) of Aloe megalacantha B and Aloe monticola R were observed. Animal model studies demonstrated the relative safety of the plants extract and phytochemistry studies showed various components. Medicinal plants used for management of diabetes mellitus in Ethiopia are worthy for further study for pharmacologically active ingredients and clinical evaluation.

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埃塞俄比亚用于管理糖尿病的药用植物的功效，安全性和植物化学：系统评价

尽管合成医学取得了巨大的发展，但药用植物仍普遍用于糖尿病的管理。这项研究综合了在埃塞俄比亚用于管理糖尿病的常用药用植物的科学证据。数据库（PubMed，Cochrane，CINAHL和Google Scholar）已被彻底寻找，证据已得到综合。三十项研究对埃塞俄比亚的19种药用植物进行了抗糖尿病活性研究。大多数研究是体内研究（25）。其他包括：临床研究（1），体外研究（2），以及体内和体外研究（2）。Trigonella foenum-graecum L.（临床研究）显示II型糖尿病患者的脂质状况有所改善。在Persea Americana和Moringa stenopetala中观察到了与格列本脲相当的血糖水平（BSL）降低效果。值得注意的是，芦荟B和芦荟R的体外半数最大抑制浓度（IC 50）被观察到。动物模型研究表明了植物提取物的相对安全性，植物化学研究表明了其各种成分。埃塞俄比亚用于管理糖尿病的药用植物值得进一步研究其药理活性成分和临床评价。