In the medical sector, various imaging methodologies or modalities (e.g. MRI, PET, CT) are used to assess the health of various parts of the bodies of patients. One such investigation is the blood flow or perfusion of the heart muscle, expressed as the (blood) flow rate normalized by the mass of the volume of interest. Currently there is no physical flow standard for the validation of quantitative perfusion measurements. This need has been addressed in the EMPIR 15HLT05 PerfusImaging project. A phantom simulating the heart muscle has been developed with the capability that it can reproducibly generate a flow profile with individual flow rates known with a relative uncertainty of about 10% (k = 2) and total flow rate known with an uncertainty of 1% (k = 2). An overview of the phantom and its validation is given. Next, a new analysis method is presented to analyse the sequence of images which are acquired when using a standard dynamic imaging protocol. It is concluded that the new, alternative approach gives results comparable to the standard analysis method.

在医疗领域，各种成像方法或方式（例如MRI，PET，CT）用于评估患者身体各个部位的健康状况。一种这样的研究是心肌的血流或灌注，表示为通过感兴趣体积的质量归一化的（血液）流速。当前，尚无用于验证定量灌注测量结果的物理流量标准。EMPIR 15HLT05 PerfusImaging项目已解决了这一需求。已开发出一种模拟心肌的幻像，其具有可再现性地生成流量曲线的能力，已知的单个流量的相对不确定度约为10％（k  = 2），而总流量的不确定性约为1％（k  = 2）。概述了幻影及其验证。接下来，提出了一种新的分析方法来分析使用标准动态成​​像协议时获取的图像序列。结论是，新的替代方法可提供与标准分析方法相当的结果。