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Synthesis of novel 1,4-oxathiine derivatives containing polyfluoroalkyl substituents at positions 2 and 6
Chemistry of Heterocyclic Compounds ( IF 1.4 ) Pub Date : 2021-02-02 , DOI: 10.1007/s10593-021-02869-8
Yaroslav S. Borodkin , Yuriy G. Shermolovich

Dehydrofluorination of bis(1,1-dihydropolyfluoroalkyl) sulfides with lithium hydroxide in morpholine occurs in a controlled manner with the formation of a new type of bis(enamine) sulfides, bis[2-(morpholin-4-yl)polyfluoroalk-1-en-1-yl]sulfanes, hydrolysis and subsequent fluorination of which leads to the production of novel fluorine-containing 1,4-oxathiine derivatives with divalent sulfur.



中文翻译:

合成在位置2和6上具有多氟烷基取代基的新型1,4-氧代嘧啶衍生物

在吗啉中用氢氧化锂对双(1,1-二氢多氟烷基)硫化物进行脱氟化氢反应,并以可控的方式发生,形成了新型的双(烯胺)硫化物,即双[2-(吗啉-4-基)聚氟烷基-1-烯基-1,4-亚砜]的水解和随后的氟化反应导致生成具有二价硫的新型含氟1,4-氧代嘧啶衍生物。

更新日期:2021-02-02
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