Microbiological culture is a key element in the diagnosis of periprosthetic joint infection (PJI). However, cultures of periprosthetic tissue do not have optimal sensitivity. One of the main reasons for this is that microorganisms are not released from the tissues, either due to biofilm formation or intracellular persistence. This study aimed to optimize tissue pretreatment methods in order to improve detection of microorganisms.

中文翻译：

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不同组织标本预处理方法对微生物培养结果的影响，可诊断假体周围感染。

微生物培养是假体周围关节感染（PJI）诊断的关键要素。但是，假体周围组织的培养物没有最佳的敏感性。造成这种情况的主要原因之一是由于生物膜的形成或细胞内的持久性，微生物没有从组织中释放出来。这项研究旨在优化组织预处理方法，以改善对微生物的检测。