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Verbascoside inhibits the epithelial‐mesenchymal transition of prostate cancer cells through high‐mobility group box 1/receptor for advanced glycation end‐products/TGF‐β pathway
Environmental Toxicology ( IF 4.5 ) Pub Date : 2021-02-01 , DOI: 10.1002/tox.23107
Chun‐Hsien Wu, Chung‐Hsien Chen, Pei‐Fang Hsieh, Yen‐Hsi Lee, Wade Wei‐Ting Kuo, Richard Chen‐Yu Wu, Chih‐Hsin Hung, Yu‐Lin Yang, Victor C. Lin

Prostate cancer has significant mortality and metastasis rate in the male. Unfortunately, effective treatment for patients with advanced prostate cancer is still lacking. Verbascoside, a phenylethanoid glycoside, displays various pharmacological properties, such as the anti‐cancer activities. The present study aimed to evaluate the effects of purified verbascoside on human prostate cancer and the associated molecular mechanisms.

中文翻译:

马鞭草苷通过高迁移率糖基化终产物/TGF-β途径的第1盒/受体抑制前列腺癌细胞的上皮-间质转化

前列腺癌在男性中具有显着的死亡率和转移率。不幸的是,仍然缺乏对晚期前列腺癌患者的有效治疗。马鞭草苷,一种苯乙酮类糖苷,具有多种药理特性,例如抗癌活性。本研究旨在评估纯化的马齿co苷对人前列腺癌的影响及其相关的分子机制。
更新日期:2021-02-01
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