Purpose

Tooth enamel might provide past chronological metabolic, nutritional status and trace metal exposure during development. Thus, the trace elements distribution embedded in tooth tissues represents an archive of the environmental conditions. The choice of biomarker is estimated as critical to the measurement of metal exposure. Natal teeth are defined as teeth being present at birth.

Methods

LA-ICP-MS provides a quantitative assessment of spatial distribution of trace elements in a natal tooth. The objective of the current study was to compare concentrations of building and other elements in a rare but reliable and valid biomarker - natal tooth.

Results

It have been reported presence of potentially toxic elements: Pb, Cu, Mn, Cd, Ni distributed in prenatally and perinatally formed enamel and dentine.

Conclusions

Analyses of deciduous enamel can provide answers into individuals’ earliest development, including critical pre- and perinatal period.

中文翻译：

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激光消融-ICPMS法测定儿童新生牙中微量元素的潜力

目的

牙釉质在发育过程中可能提供过去的时间代谢，营养状况和微量金属暴露。因此，嵌入牙组织中的微量元素分布代表了环境状况的档案。估计生物标志物的选择对金属暴露的测量至关重要。新生牙定义为出生时就存在的牙齿。

方法

LA-ICP-MS可定量评估新生牙中微量元素的空间分布。本研究的目的是比较一种罕见但可靠且有效的生物标记物-生牙中建筑物和其他元素的浓度。

结果

据报道存在潜在的有毒元素：Pb，Cu，Mn，Cd，Ni分布在产前和产前形成的牙釉质和牙本质中。

结论

乳牙釉质的分析可以为个体的早期发育（包括关键的产前和围产期）提供答案。