Research Development, Optimization and Modifications of Anti-cancer Peptides,Mini-Reviews in Medicinal Chemistry

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Research Development, Optimization and Modifications of Anti-cancer Peptides
Mini-Reviews in Medicinal Chemistry ( IF 3.3 ) Pub Date : 2020-12-31 , DOI: 10.2174/1389557520666200729163146
Zhi-Gang Sun ₁ , Liang-Hui Zhao ₂ , Stacy Mary Yeh ₃ , Zhi-Na Li ₁ , Xin Ming ₃

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Anti-cancer peptides play an important role in the area of cancer inhibition. A variety of anti- cancer peptides have emerged through the extraction and structural modification of peptides from biological tissues. This review provides the research background of anti-cancer peptides, the introduction of the mechanism of anti-cancer peptides for inhibition of cancers, the discovery and development along with optimization and modifications of these peptides in the clinical application. In conclusion, it can be said that anti-cancer peptides will play a major role in the future oncologic clinic.

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