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Advances in Research on the Preparation and Biological Activity of Maslinic Acid
Mini-Reviews in Medicinal Chemistry ( IF 3.3 ) Pub Date : 2020-12-31 , DOI: 10.2174/1389557520666200722134208
Jianqiang Deng 1 , Huiyun Wang 2 , Xiaodong Mu 1 , Xiuting He 1 , Fenglan Zhao 1 , Qingguo Meng 1
Affiliation  

Maslinic acid, a pentacyclic triterpene acid, is mainly isolated from olives. Maslinic acid and its derivatives exhibit a broad range of biological properties, such as anti-inflammatory, anticancer, anti-diabetic, antimicrobial, neuroprotective and hepatoprotective activities. In this minireview, the progress of research on maslinic acid with regard to its bioactivities, extraction, semisynthetic preparation and patents is reported. The relationships between the structure and the activity of maslinic acid and its derivatives are also discussed.



中文翻译:

山楂酸的制备及其生物活性研究进展

Maslinic酸是一种五环三萜烯酸,主要从橄榄中分离出来。山楂酸及其衍生物具有广泛的生物学特性,例如抗炎,抗癌,抗糖尿病,抗微生物,神经保护和保肝活性。在本小型审查中,报告了有关山楂酸的生物活性,提取,半合成制备和专利方面的研究进展。还讨论了山楂酸及其衍生物的结构与活性之间的关系。

更新日期:2021-01-29
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