Aim. This systematic review aimed to investigate the effect of different breathing exercises on respiratory muscle function, 6-minute walk test (6MWT), and quality of life (QoL) in patients with chronic obstructive pulmonary disease (COPD). Methods. We searched online databases including PubMed, Embase, Web of Science, Cochrane Library, and Ovid for randomized controlled trials that assessed the efficacy of breathing exercises on patients with COPD. Patient outcome parameters included changes in respiratory muscle function, 6MWT, and QoL. The Cochrane Collaboration tool was used to assess the risk of bias for each included study. Subgroup analyses concerning different interventions and outcome measurements were conducted as necessary. PROSPERO registration number is CRD42018118367. Results. A total of 17 studies were included for final analysis. Meta-analysis based on the relevant studies showed that breathing exercises had a significant total effect on pulmonary function PImax (mean difference (MD) = 8.65, 95% confidence interval (CI) 3.13–14.16, ), as well as 6MWT (MD = 27.70, 95% CI 5.45–49.94, ) in patients with COPD. Conclusions. This systematic review summarized the use of breathing exercises for treating patients with COPD. Breathing exercises were found to be an effective tool for treating patients with COPD by improving inspiratory muscle strength and 6MWT. However, breathing exercises showed no significant improvements on the QoL of patients with COPD.

中文翻译：

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呼吸练习如何影响慢性阻塞性肺病患者的呼吸肌和生活质量？系统回顾和荟萃分析


目的。本系统评价旨在探讨不同呼吸练习对慢性阻塞性肺疾病 (COPD) 患者呼吸肌功能、6 分钟步行试验 (6MWT) 和生活质量 (QoL) 的影响。方法。我们检索了包括 PubMed、Embase、Web of Science、Cochrane Library 和 Ovid 在内的在线数据库，以查找评估呼吸练习对 COPD 患者疗效的随机对照试验。患者结果参数包括呼吸肌功能、6MWT 和 QoL 的变化。 Cochrane 协作工具用于评估每项纳入研究的偏倚风险。必要时进行有关不同干预措施和结果测量的亚组分析。 PROSPERO 注册号为 CRD42018118367。结果。总共纳入17项研究进行最终分析。基于相关研究的荟萃分析表明，呼吸练习对肺功能PImax有显着的总体影响（平均差（MD）= 8.65，95％置信区间（CI）3.13-14.16， ），以及 6MWT（MD = 27.70，95% CI 5.45–49.94，）患有慢性阻塞性肺病（COPD）的患者。结论。本系统综述总结了呼吸练习在治疗慢性阻塞性肺病患者中的应用。 研究发现，呼吸练习可改善吸气肌力量和 6MWT，是治疗 COPD 患者的有效工具。然而，呼吸练习对慢性阻塞性肺病患者的生活质量没有显着改善。