The elongation of a tank-treading red blood cell (RBC) under shear flow was numerically simulated to understand its mechanical characteristics. The boundary element method was used to couple the viscoelastic deformation of the cell membrane and viscous flow of the surrounding fluids. Accordingly, it was found that elongation deformation and inclination angle, which depend on the cell membrane's viscoelasticity, inner viscosity, and swelling ratio, were related to the fluid traction difference between the suspending and RBC inner fluids. When the viscosity of an RBC is compatible with the suspending fluid, the elongation index responding fluid shear stress is similar to the responding external loads in the optical tweezers stretch, with different elongation mechanics. By identifying the viscoelasticity of the cell membrane to reproduce published experimental data, the strain hardening elasticity of the cell membrane was identified by modifying the model developed by Skalak et al. (Biophys. J., Vol. 13, pp. 245-264, 1973); the exponential form of Fung (Biorheology, Vol. 10, pp. 139-155, 1973) successfully expressed the stronger strain hardening behavior for the latter deformation regime. These results indicate the applicability of the shear flow experiments as a stretch testing method to measure the viscoelasticity of the cell membrane.

通过数值模拟坦克横断面红细胞（RBC）在剪切流作用下的伸长，以了解其力学特性。边界元方法被用来耦合细胞膜的粘弹性变形和周围流体的粘性流动。因此，发现取决于细胞膜的粘弹性，内部粘度和溶胀率的伸长变形和倾斜角与悬浮液和RBC内部流体之间的流体牵引力差异有关。当RBC的粘度与悬浮液相容时，伸长系数响应的流体剪切应力与光镊拉伸中的响应的外部载荷相似，但具有不同的伸长机理。通过鉴定细胞膜的粘弹性以复制已发表的实验数据，通过修改Skalak等人开发的模型来鉴定细胞膜的应变硬化弹性。（Biophys.J。，第13卷，第245-264页，1973）；Fung的指数形式（Biorheology，第10卷，第139-155页，1973年）成功地表达了后一种变形形式的更强的应变硬化行为。这些结果表明剪切流实验作为测量细胞膜粘弹性的拉伸测试方法的适用性。1973年）成功地表达了后者变形状态下更强的应变硬化行为。这些结果表明剪切流实验作为测量细胞膜粘弹性的拉伸测试方法的适用性。1973年）成功地表达了后者变形状态下更强的应变硬化行为。这些结果表明剪切流实验作为测量细胞膜粘弹性的拉伸测试方法的适用性。