Crop rotation is a simple and effective part of an Integrated Weed Management (IWM) system. This approach makes it possible to rotate herbicides with different modes of action (MOA), avoiding or postponing herbicide resistance. Besides all the known advantages and benefits, it is still not widely used in maize (Zea mays L.) production. In Serbia, about 20% of total maize production is a continuous cropping. The aim of this research was to test the benefits of growing maize in crop rotation with winter wheat (Triticum vulgare L.) compared with a continuous cropping, combined with pre-emergence herbicide application. Field trials started in 2009, and five maize-winter wheat rotations have been completed. Weeds were controlled with a herbicide mixture of isoxaflutole and S-metolachlor, applied at either the full label rate or half rate, while one plot was kept weed free (manually), and one was a control. Integrating crop rotation and PRE herbicides decreased the biomass of weeds and their density by 98% and 99%, respectively. In continuous maize, perennial weeds became dominant after the first rotation. Crop rotation significantly influenced maize productive parameters, decreasing the variation in leaf area index and grain yield, increasing values with the number of cycles. The biggest differences in the analyzed parameters were observed in 2015, 2017 and 2019, indicating many positive long-term benefits of crop rotation on maize leaf area index and grain yield.

轮作是综合杂草管理（IWM）系统的简单有效的组成部分。这种方法使旋转具有不同作用模式（MOA）的除草剂成为可能，从而避免或推迟了除草剂的耐药性。除了所有已知的优点和好处，它仍未广泛用于玉米（Zea mays L.）生产中。在塞尔维亚，约占玉米总产量的20％是连作作物。这项研究的目的是检验使用冬小麦（Triticum vulgare）种植玉米在作物轮作中的益处。L.）与连作结合，并在出苗前使用除草剂。田间试验于2009年开始，已经完成了5个玉米－冬季小麦轮作。用异黄腐酚和异丙甲草胺的除草剂混合物控制杂草，以全标记率或半剂量施用，而其中一个地块（手动）保持无杂草，其中一个作为对照。轮作和PRE除草剂的整合使杂草的生物量及其密度分别降低了98％和99％。在连续玉米中，多年生杂草在第一次轮作后占主导地位。轮作显着影响玉米的生产参数，减少叶面积指数和谷物产量的变化，并随着循环次数的增加而增加。在2015年，2017年和2019年观察到分析参数的最大差异，