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Stem cells from human exfoliated deciduous teeth ameliorate concanavalin A-induced autoimmune hepatitis by protecting hepatocytes from apoptosis.
World Journal of Stem Cells ( IF 3.6 ) Pub Date : 2021-1-29 , DOI: 10.4252/wjsc.v12.i12.1623
Yi-Kun Zhou , Ling-Su Zhu , Hua-Ming Huang , Sheng-Jie Cui , Ting Zhang , Yan-Heng Zhou , Rui-Li Yang

Autoimmune hepatitis is a serious autoimmune liver disease that threatens human health worldwide, which emphasizes the urgent need to identify novel treatments. Stem cells from human exfoliated deciduous teeth (SHED), which are easy to obtain in a non-invasive manner, show pronounced proliferative and immunomodulatory capacities.

中文翻译:

通过保护肝细胞免于凋亡,人类脱落乳牙的干细胞可减轻伴刀豆球蛋白A诱导的自身免疫性肝炎。

自身免疫性肝炎是一种严重的自身免疫性肝病,威胁着全世界的人类健康,强调了寻找新疗法的迫切需要。易于以非侵入性方式获得的人脱落乳牙(SHED)的干细胞显示出明显的增殖和免疫调节能力。
更新日期:2021-01-30
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