Applications of DNA-nanozyme-based sensors,Analyst

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Applications of DNA-nanozyme-based sensors
Analyst ( IF 3.6 ) Pub Date : 2021-1-12 , DOI: 10.1039/d0an02368j
Renzhong Yu _{1,

2,

3,

4} , Rui Wang _{1,

2,

3,

4} , Zhaoyin Wang _{1,

2,

3,

4} , Qinshu Zhu _{1,

2,

3,

4,

5} , Zhihui Dai _{1,

2,

3,

4,

5}

Affiliation

Since the discovery of the enzyme-like activities of nanomaterials, the study of nanozymes has become one of the most popular research frontiers of diverse areas including biosensors. DNA also plays a very important role in the construction of biosensors. Thus, the idea of combined applications of nanozymes with DNA (DNA-nanozyme) is very attractive for the development of nanozyme-based biosensors, which has attracted considerable interest of researchers. To date, many sensors based on DNA-functionalized or templated nanozymes have been reported for the detection of various targets and highly accelerated the development of nanozyme-based sensors. In this review, we summarize the main applications and advances of DNA-nanozyme-based sensors. Additionally, perspectives and challenges are also discussed at the end of the review.

中文翻译：

DNA纳米酶基传感器的应用

自从发现纳米材料的类酶活性以来，对纳米酶的研究已成为包括生物传感器在内的各个领域最受欢迎的研究前沿之一。DNA在生物传感器的构建中也起着非常重要的作用。因此，纳米酶与DNA（DNA-纳米酶）结合应用的想法对于基于纳米酶的生物传感器的开发非常有吸引力，这引起了研究人员的极大兴趣。迄今为止，已经报道了许多基于DNA功能化或模板化纳米酶的传感器，用于检测各种目标，并极大地促进了基于纳米酶的传感器的开发。在这篇综述中，我们总结了基于DNA纳米酶的传感器的主要应用和进展。此外，在审查结束时还将讨论观点和挑战。

更新日期：2021-01-28

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