The National Institute for Health and Care Excellence (NICE) recently published its draft updated guideline on the diagnosis and management of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). NICE concluded that ME/CFS is a complex multisystem chronic medical condition for which graded exercise therapy should not be used and cognitive behavioural therapy is only a supportive therapy and not a treatment or cure. The draft guidance also highlighted the unreliability of subjective outcome measures in non-blinded trials. High quality randomised controlled ME/CFS trials are now needed to find pharmacological treatments that lead to substantial objective improvement and restore the ability to work.

美国国家健康与护理卓越研究所 (NICE) 最近发布了关于肌痛性脑脊髓炎/慢性疲劳综合征 (ME/CFS) 诊断和管理的更新指南草案。NICE 得出结论，ME/CFS 是一种复杂的多系统慢性疾病，不应使用分级运动疗法，认知行为疗法只是一种支持疗法，而不是治疗或治愈。该指南草案还强调了非盲试验中主观结果测量的不可靠性。现在需要进行高质量的随机对照 ME/CFS 试验，以找到能够显着客观改善并恢复工作能力的药物治疗。