Abstract

Background and objective: Knee osteoarthritis is a disabling disease, causing pain and reduced function. Orthoses are used to manage this problem, including knee braces and lateral wedge insoles. However, there is still controversy on which type of intervention is more effective. This systematic review aimed to evaluate the effect of knee braces and lateral wedge insoles and compare their clinical outcomes on individuals with medial knee osteoarthritis.

Methods: We conducted the search strategy based on the population, intervention, comparison, and outcome (PICO) method. We searched with PubMed, EMBASE, Web of Science, and Scopus databases for the related studies. The articles’ quality assessment was done based on the modified Downs and Black checklist.

Results: Totally, we chose 32 controlled trials, including 1.849 participants, for the final evaluation. Almost two-thirds of the studies had a moderate quality. The overall outcome suggested that both interventions had improved pain and function. The difference between both interventions on pain reduction was not significant (standardized mean difference= -0.12, 95% confidence interval= -0.34 to 0.1) based on meta-analysis.

Conclusion: Both knee brace and lateral wedge insole can improve pain and function in people with knee osteoarthritis. Using either separately or both of them together are effective.

摘要

背景与目的：膝骨关节炎是一种致残性疾病，引起疼痛和功能下降。矫形器用于解决此问题，包括膝关节矫正器和侧楔形鞋垫。但是，关于哪种类型的干预更有效仍存在争议。该系统评价旨在评估护膝和外侧楔形鞋垫的效果，并比较其对内侧膝骨关节炎患者的临床疗效。

方法：我们基于人群，干预，比较和结果（PICO）方法进行了搜索策略。我们使用PubMed，EMBASE，Web of Science和Scopus数据库进行了搜索，以进行相关研究。文章的质量评估是基于修改后的Downs and Black清单进行的。

结果：总共，我们选择了32项对照试验（包括1.849名参与者）作为最终评估。几乎三分之二的研究质量中等。总体结果表明，两种干预措施均改善了疼痛和功能。基于荟萃分析，两种疼痛减轻干预措施之间的差异均不显着（标准化平均差异= -0.12，95％置信区间= -0.34至0.1）。

结论：膝关节支撑和外侧楔形鞋垫均可改善膝关节骨关节炎患者的疼痛和功能。单独使用或同时使用它们是有效的。