The accurate processing of temporal information is of critical importance in everyday life. Yet, psychophysical studies in humans have shown that the perception of time is distorted around saccadic eye movements. The neural correlates of this misperception are still poorly understood. Behavioral and neural evidence suggest that it is tightly linked to other known perisaccadic modulations of visual perception. To further our understanding how temporal processing is affected by saccades, we studied the representations of brief visual time intervals during fixation and saccades in area V4 of two awake macaques. We presented random sequences of vertical bar stimuli and extracted neural responses to double-pulse stimulation at varying inter-stimulus intervals. Our results show that temporal information about very brief intervals of as brief as 20 ms is reliably represented in the multi-unit activity in area V4. Response latencies were not systematically modulated by the saccade. However, a general increase in perisaccadic activity altered the ratio of response amplitudes within stimulus pairs compared to fixation. In line with previous studies showing that the perception of brief time intervals is partly based on response levels, this may be seen as a possible correlate of the perisaccadic misperception of time.

中文翻译：

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猕猴区域 V4 中时间信息的 Perisaccadic 编码

时间信息的准确处理在日常生活中至关重要。然而，对人类的心理物理学研究表明，时间的感知会随着扫视的眼球运动而扭曲。这种误解的神经相关性仍然知之甚少。行为和神经证据表明，它与其他已知的视觉感知周跳调制密切相关。为了进一步了解眼跳如何影响时间处理，我们研究了两只清醒猕猴的 V4 区域的注视和眼跳期间短暂视觉时间间隔的表示。我们呈现了垂直条刺激的随机序列，并以不同的刺激间隔提取了对双脉冲刺激的神经反应。我们的结果表明，关于短至 20 毫秒的非常短的时间间隔的时间信息在区域 V4 的多单元活动中得到了可靠的表示。响应潜伏期没有系统地由眼跳调节。然而，与固定相比，周跳活动的普遍增加改变了刺激对内反应幅度的比率。与之前的研究表明，对短暂时间间隔的感知部分基于响应水平，这可能被视为可能与周跳时间错误感知相关。