Despite significant progress in reaching some milestones of the United Nations Sustainable Development Goals, neonatal and early infant morbidity and mortality remain high, and maternal health remains suboptimal in many countries. Novel and improved preventative strategies with the potential to benefit pregnant women and their infants are needed, with maternal and neonatal immunization representing effective approaches. Experts from immunology, vaccinology, infectious diseases, clinicians, industry, public health, and vaccine-related social sciences convened at the 5th International Neonatal and Maternal Immunization Symposium (INMIS) in Vancouver, Canada, from 15 to 17 September 2019. We critically evaluated the lessons learned from recent clinical studies, presented cutting-edge scientific progress in maternal and neonatal immunology and vaccine development, and discussed maternal and neonatal immunization in the broader context of infectious disease epidemiology and public health. Focusing on practical aspects of research and implementation, we also discussed the safety, awareness, and perception of maternal immunization as an existing strategy to address the need to improve maternal and neonatal health worldwide. The symposium provided a comprehensive scientific and practical primer as well as an update for all those with an interest in maternal and neonatal infection, immunity, and vaccination. The summary presented here provides an update of the current status of progress in maternal and neonatal immunization.

中文翻译：

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第五届国际新生儿和孕产妇免疫研讨会（INMIS 2019）：确保下一代的保护


尽管在实现联合国可持续发展目标的一些里程碑方面取得了重大进展，但许多国家的新生儿和早期婴儿发病率和死亡率仍然很高，孕产妇健康状况仍然不佳。需要有可能使孕妇及其婴儿受益的新颖和改进的预防策略，其中孕产妇和新生儿免疫是有效的方法。来自免疫学、疫苗学、传染病、临床医生、工业、公共卫生和疫苗相关社会科学的专家于 2019 年 9 月 15 日至 17 日在加拿大温哥华召开了第五届国际新生儿和孕产妇免疫研讨会 (INMIS)。我们严格评估了从最近的临床研究中汲取的经验教训，介绍了孕产妇和新生儿免疫学和疫苗开发方面的前沿科学进展，并在传染病流行病学和公共卫生的更广泛背景下讨论了孕产妇和新生儿免疫问题。重点关注研究和实施的实际方面，我们还讨论了孕产妇免疫接种的安全性、意识和看法，作为解决改善全球孕产妇和新生儿健康需求的现有战略。此次研讨会为所有对孕产妇和新生儿感染、免疫和疫苗接种感兴趣的人们提供了全面的科学实用入门知识和最新信息。这里的总结提供了孕产妇和新生儿免疫接种的最新进展状况。