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Stress as cause of signs and symptoms of pseudo‐Cushing’s syndrome in buffy‐tufted marmosets (Callithrix aurita)
Journal of Medical Primatology ( IF 0.8 ) Pub Date : 2021-01-28 , DOI: 10.1111/jmp.12514
Heloísa Orsini 1 , Viviane B D Castellano 1 , Hanna S Kokubun 1 , Karla A R Lopes 1 , Nádia M R C Velho 1
Affiliation  

Hyperadrenocorticism is a medical condition caused by the increase in cortisol production by the cortex of the adrenal gland. Although infrequently described in most animal species, its naturally occurring form, called Cushing's syndrome, is the most prevalent endocrinopathy in dogs. Cushing's syndrome is also present in humans and might be confused with the pseudo‐Cushing's syndrome (PCS), rarely described in animals. PCS shares many of the clinical and biochemical features of Cushing's syndrome. However, the hypercortisolemia seen is usually idiopathic and, in some circumstances, associated with psychological disruptions. This report describes PCS‐like disorder in two marmosets Callithrix aurita that were exposed to environmental changes, suggesting stress as the main cause of the process and reviewing the mechanisms involved in the pathogeny of the two syndromes.

中文翻译:

压力是棕黄色绒猴 (Callithrix aurita) 伪库欣综合征体征和症状的原因

肾上腺皮质功能亢进是一种由肾上腺皮质产生的皮质醇增加引起的医学病症。尽管在大多数动物物种中很少被描述,但其自然发生的形式,称为库欣综合征,是狗中最普遍的内分泌病。库欣综合征也存在于人类中,可能与在动物中很少描述的假库欣综合征 (PCS) 混淆。PCS 具有库欣综合征的许多临床和生化特征。然而,所见的高皮质醇血症通常是特发性的,在某些情况下,与心理障碍有关。这份报告描述了两只狨猴Callithrix aurita 的PCS 样疾病 暴露于环境变化,表明压力是这一过程的主要原因,并回顾了这两种综合征的发病机制。
更新日期:2021-03-17
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