Abstract

The article is devoted to the pharmaceutical substance of glucose with sodium chloride connected by a crystal lattice into a single cocrystal in a ratio identical to the composition of medicinal solutions of glucose with sodium chloride (NaCl). Currently, these solutions are obtained from two substances of glucose and sodium chloride, which creates certain difficulties in the production of substances and solutions, complicating their technology and the cost of drugs. The proposed pharmaceutical substance is developed based on a double compound (DC) of glucose with sodium chloride, characterized by a high crystallization rate and solubility. The main parameters of the technological mode of cocrystallization of glucose with NaCl for inclusion in the production line for the production of crystalline glucose are determined. The high solubility of the substance in comparison with other types of glucose is shown.

中文翻译：

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氯化钠与葡萄糖共结晶的研究

摘要

该制品致力于葡萄糖的药用物质，其氯化钠通过晶格连接成单一的共晶，其比例与葡萄糖与氯化钠（NaCl）的药用溶液的组成相同。目前，这些溶液是从葡萄糖和氯化钠这两种物质中获得的，这给物质和溶液的生产带来了一定的困难，使它们的技术和药物成本变得复杂。所提出的药物是基于葡萄糖与氯化钠的双重化合物（DC）开发的，其特征在于高结晶速率和溶解性。确定了葡萄糖与NaCl共结晶的技术模式的主要参数，以包括在生产结晶葡萄糖的生产线中。