Doxorubicin (DOX), an anthracycline drug, is widely used for the treatment of several cancers like osteosarcoma, cervical carcinoma, breast cancer, etc. DOX lacks target specificity; thereby it also affects normal cells thus resulting in several side-effects. A drug delivery system (DDS) can be used to deliver the drug in a controlled and sustained manner at a targeted site within the body. Various DDS like nanoemulsions, polymeric nanoparticles, and liposomes are used for loading DOX. Alginate, a polysaccharide is widely used for fabricating DDS due to its biodegradable and bio-compatible properties. Alginates, in combination with other biomaterials, have been extensively used as a novel drug delivery carrier for DOX. Alginate provides a platform for drug delivery in different forms like hydrogels, nanogels, nanoparticles, microparticles, graphene oxide systems, magnetic systems, etc. Herein, we briefly describe alginate in combination with other materials as a nanocarrier for targeted delivery of DOX for anti-cancer treatment.

蒽环类药物阿霉素（DOX）被广泛用于治疗多种癌症，例如骨肉瘤，宫颈癌，乳腺癌等。DOX缺乏目标特异性；因此，它也影响正常细胞，从而产生若干副作用。药物输送系统（DDS）可用于以受控和持续的方式在体内目标部位输送药物。各种DDS（如纳米乳剂，聚合物纳米颗粒和脂质体）用于加载DOX。海藻酸盐，一种多糖，由于其具有可生物降解和生物相容性，因此被广泛用于制造DDS。海藻酸盐与其他生物材料的结合已被广泛用作DOX的新型药物输送载体。海藻酸盐提供了以不同形式递送药物的平台，例如水凝胶，纳米凝胶，纳米颗粒，微粒，氧化石墨烯系统，磁性系统等。 在本文中，我们简要描述了藻酸盐与其他材料的组合作为纳米载体，用于靶向递送DOX以进行抗癌治疗。