A novel wound dressing based on chitosan (CS) and gelatin (GL) was prepared and the effect of potato-starch (ST), sesame oil (SO) and banana peel powder (BPP) on the physical and mechanical properties, cytocompatibility and wound healing capability of the films were evaluated. The mechanical results showed that the samples containing 5 wt% of potato-starch and 7 wt% of banana peel powder had the best mechanical properties (Elastic Modulus of 1930 MPa and Tensile Strength of 58.2 MPa). The scanning electron micrographs presented the uniform distribution of banana peel powder within the polymeric matrix up to 7 wt% of banana peel powder. By Adding banana peel powder to the film composition, the antibacterial activity of the films against E. coli and S. aureus bacteria increased. The MTT assay results revealed that the films containing banana peel powder had no toxicity and never caused cell death. In vivo experiments, using an animal model, demonstrated that the proliferation of blood vessels and angiogenesis along with connective tissues formations were accelerated considerably by the samples prepared in this study.

制备了一种基于壳聚糖（CS）和明胶（GL）的新型伤口敷料，并研究了马铃薯淀粉（ST），芝麻油（SO）和香蕉皮粉（BPP）对物理机械性能，细胞相容性和伤口的影响评价了膜的愈合能力。力学结果表明，含有5 wt％的马铃薯淀粉和7 wt％的香蕉皮粉末的样品具有最佳的机械性能（1930 MPa的弹性模量和58.2 MPa的拉伸强度）。扫描电子显微照片显示了香蕉皮粉在聚合物基质中的均匀分布，直至香蕉皮粉的7 wt％。通过将香蕉皮粉末添加到薄膜组合物中，薄膜对大肠杆菌和金黄色葡萄球菌的抗菌活性增加。MTT分析结果表明，含有香蕉皮粉末的薄膜没有毒性，也从未引起细胞死亡。使用动物模型进行的体内实验表明，通过本研究中制备的样品，血管的增殖和血管生成以及结缔组织的形成得到了显着加速。