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A Novel Strategy for the Microbial Removal of Heavy Metals: Cell-surface Display of Peptides
Biotechnology and Bioprocess Engineering ( IF 2.5 ) Pub Date : 2021-01-26 , DOI: 10.1007/s12257-020-0218-z
Yuanyuan Wang , Vidhya Selvamani , Ik-Keun Yoo , Tae Wan Kim , Soon Ho Hong

Cell surface engineering is a rapidly developing technology of microorganism that achieves modification of cell surface function by joining external functional peptides with surface anchoring proteins, for example, Outer Member Protein (OMP). On account of these proteins possessing metal responsive motifs, they can be specifically used for metal adsorption and dissociation. To elucidate the problems caused by heavy metals and develop various technologies for their removel or recovery, various metal-binding proteins/peptides fused on microorganism cell surface have been applied as novel methods. During the past few years, bacterial cell surface display strategy has received growing attention for their availability to eliminate heavy metals. In this paper, the existing problems, progress, and suggestions for furture of the peptide displaying system are summarized.



中文翻译:

微生物去除重金属的新策略:肽的细胞表面显示

细胞表面工程是一种快速发展的微生物技术,它通过将外部功能肽与表面锚定蛋白(例如外成员蛋白(OMP))结合来实现细胞表面功能的修饰。由于这些蛋白质具有金属反应性基序,因此它们可以专门用于金属吸附和解离。为了阐明由重金属引起的问题并开发用于去除或回收重金属的各种技术,已将融合在微生物细胞表面上的各种金属结合蛋白/肽用作新方法。在过去的几年中,细菌细胞表面展示策略因其可用于消除重金属而受到越来越多的关注。本文中存在的问题,进展,

更新日期:2021-01-28
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