ABSTRACT

Background: This study aims to compare the predictive value of all comprehensive geriatric assessment (CGA) parameters with the predictive value of frailty assessment (with Edmonton Frailty Scale (EFS) and Fried Frailty Index (FFI)) for long-term mortality, in older adults.

Methods: A total of 967 patients were included, consecutively. At the first admission, age, gender, comorbidities, number of drugs, and laboratory values of the patients were recorded. Each patient underwent CGA which consisted of anthropometric measurements, functional, cognitive, mood, nutritional, gait, fall, sleep duration, and frailty assessment. Fifty-seven months after the first admission, CGA parameters were analyzed to determine their predictive abilities on long-term mortality due to all causes, comparatively.

Results: The median age was 73 years (range 65–94 years). The median follow-up time was 39.9 months (range 0.5–57.3 months). Serum albumin level, FFI, EFS, instrumental activity of daily living (IADL) score, and walking time were the best predictors of mortality. There was no significant difference between these parameters in predicting mortality.

Conclusion: FFI and EFS have similar predictive value for mortality. In busy clinical practice, a new index based on IADL, walking time, and serum albumin level may be an alternative of frailty assessment for predicting mortality.

摘要

背景：本研究旨在比较老年人的所有综合老年医学评估（CGA）参数的预测价值与脆弱性评估（使用埃德蒙顿脆弱性量表（EFS）和油炸脆弱性指数（FFI））对长期死亡率的预测价值成年人。

方法：共纳入967例患者。首次入院时，记录患者的年龄，性别，合并症，药物数量和实验室检查值。每位患者均接受了CGA，包括人体测量，功能，认知，情绪，营养，步态，跌倒，睡眠时间和体弱评估。首次入院后的57个月，对CGA参数进行了分析，以比较确定其对由各种原因引起的长期死亡率的预测能力。

结果：中位年龄为73岁（范围65-94岁）。中位随访时间为39.9个月（范围0.5-57.3个月）。血清白蛋白水平，FFI，EFS，日常器械活动（IADL）评分和步行时间是死亡率的最佳预测指标。这些参数在预测死亡率方面没有显着差异。

结论：FFI和EFS对死亡率具有相似的预测价值。在繁忙的临床实践中，基于IADL，步行时间和血清白蛋白水平的新指标可能是脆弱评估以预测死亡率的替代方法。