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Suicidal ideation, attempt, and its associated factors among HIV/AIDS patients in Africa: a systematic review and meta-analysis study
International Journal of Mental Health Systems ( IF 3.1 ) Pub Date : 2021-01-23 , DOI: 10.1186/s13033-021-00437-3
Mogesie Necho , Mekonnen Tsehay , Yosef Zenebe

Suicidal ideation and suicidal attempt are warning signs for and determine the prognosis of completed suicide. These suicidal behaviors are much more pronounced in people living with HIV/AIDS. Despite this, there is a scarcity of aggregate evidence in Africa. This study was therefore aimed to fill this gap. we extensively searched Psych-info, PubMed, Scopus, and EMBASE to obtain eligible studies. Further screening for a reference list of articles was also done. Meta XL package was used to extract data and the Stata-11 was also employed. Cochran’s Q- and the Higgs I2 test were engaged to check heterogeneity. Sensitivity and subgroup analysis were implemented. Egger’s test and funnel plots were used in detecting publication bias. The pooled prevalence of suicidal ideation was 21.7% (95% CI 16.80, 26.63). The pooled prevalence of suicidal ideation in Ethiopia, Nigeria, Uganda, and South Africa was 22.7%, 25.3%, 9.8%, and 18.05% respectively. The pooled prevalence of suicidal ideation was larger; 27.7% in studies that used Composite International Diagnostic Interview (CIDI) than Mini-international Neuropsychiatric Interview (MINI); 16.96%. Moreover, the prevalence of suicidal ideation in studies with a sample size of < 400 was 23.42% whereas it was 18.3% in studies with a sample size ≥ of 400 participants. The pooled prevalence of suicidal attempts in this study was 11.06% (95% CI 6.21, 15.92). A suicidal attempt was higher in Ethiopia (16.97%) and Nigeria (16.20%) than Uganda (3.51%). This pooled prevalence of suicidal attempt was higher among studies that used a smaller sample (< 400 participants) (15.5%) than studies that used a larger sample size (≥ 400 participants) (8.4%). The pooled prevalence of suicidal attempt was 3.75%, and 16.97% in studies that used MINI and CIDI respectively. Our narrative synthesis revealed that advanced stages of AIDS, co-morbid depression, perceived HIV stigma, and poor social support was among the factors strongly associated with suicidal ideation and attempt. The pooled magnitude of suicidal ideation and attempt was high and factors like advanced stages of AIDS, co-morbid depression, perceived stigma, and poor social support were related to it. Clinicians should be geared towards this mental health problem of HIV patients during management.

中文翻译:

非洲艾滋病毒/艾滋病患者的自杀意念,尝试及其相关因素:系统评价和荟萃分析研究

自杀意念和自杀企图是完成自杀的警告信号,并确定自杀的预后。这些自杀行为在艾滋病毒/艾滋病感染者中更为明显。尽管如此,非洲仍缺乏汇总证据。因此,本研究旨在填补这一空白。我们广泛搜索了Psych-info,PubMed,Scopus和EMBASE以获得合格的研究。还对文章的参考清单进行了进一步筛选。使用Meta XL软件包提取数据,也使用Stata-11。进行了Cochran的Q和希格斯I2检验以检查异质性。进行敏感性和亚组分析。Egger检验和漏斗图用于检测出版偏倚。自杀意念的合并患病率为21.7%(95%CI 16.80,26.63)。埃塞俄比亚,尼日利亚,乌干达和南非的自杀意念合并患病率分别为22.7%,25.3%,9.8%和18.05%。自杀意念的合并患病率较高;使用综合国际诊断访谈(CIDI)的研究比进行迷你国际神经精神病访谈(MINI)的研究高27.7%;16.96%。此外,在样本量小于400的研究中,自杀意念的发生率为23.42%,而样本量≥400的研究中的自杀意念的发生率为18.3%。这项研究中自杀未遂的总患病率为11.06%(95%CI 6.21,15.92)。埃塞俄比亚(16.97%)和尼日利亚(16.20%)的自杀未遂率高于乌干达(3.51%)。在使用较小样本(<400名参与者)的研究中,自杀企图的普遍发生率较高(15。比使用较大样本量的研究(≥400名参与者)(8.4%)高出5%)。在使用MINI和CIDI的研究中,自杀未遂的总患病率分别为3.75%和16.97%。我们的叙述性综合显示,艾滋病晚期,合并症,抑郁症,艾滋病毒的耻辱感以及社会支持差是与自杀意念和企图强烈相关的因素。自杀意念和企图的综合程度很高,并且与艾滋病晚期,合并病性抑郁,知觉的污名和社会支持差等因素有关。在管理过程中,临床医生应针对艾滋病毒患者的心理健康问题。我们的叙述综合表明,艾滋病的晚期,合并症,抑郁症,艾滋病毒的耻辱感以及社会支持差是与自杀意念和企图强烈相关的因素。自杀意念和企图的综合程度很高,并且与艾滋病晚期,合并病性抑郁,知觉的污名和社会支持差等因素有关。在管理过程中,临床医生应针对艾滋病毒患者的心理健康问题。我们的叙述性综合显示,艾滋病晚期,合并症,抑郁症,艾滋病毒的耻辱感以及社会支持差是与自杀意念和企图强烈相关的因素。自杀意念和企图的综合程度很高,并且与艾滋病晚期,合并病性抑郁,知觉的污名和社会支持差等因素有关。在管理过程中,临床医生应针对艾滋病毒患者的心理健康问题。与社会支持差有关。在管理过程中,临床医生应针对艾滋病毒患者的心理健康问题。与社会支持差有关。在管理过程中,临床医生应针对艾滋病毒患者的心理健康问题。
更新日期:2021-01-24
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