The spread of both infectious and noninfectious diseases through wildlife populations is of increasing concern. Neoplastic diseases are rarely associated with population-level impacts in wildlife; however, impacts on individual health can be severe and might reflect deteriorating environmental conditions. An adult male free-ranging Blanding’s turtle (Emydoidea blandingii) originally captured in 2005 and deemed healthy, was recaptured in 2018 with a 1 × 1.5 cm intra-oral broad-based right mandibular mass. An excisional biopsy was performed, and histopathology revealed squamous cell carcinoma (SCC). Consensus herpesvirus PCR identified a novel herpesvirus (proposed name Emydoidea herpesvirus 2 [EBHV-2]) within the tumor. EBHV-2 shares 85% sequence homology with Terrapene herpesvirus 2 (TerHV-2), a herpesvirus linked to fibropapillomas in eastern box turtles (Terrapene carolina carolina). Virus-associated fibropapillomas have been identified in multiple marine turtle species and have had debilitating effects on their populations, but to date, virus-associated SCCs are rarely reported.

传染病和非传染病通过野生动物种群传播越来越受到关注。肿瘤疾病很少与野生动物的种群水平影响相关；然而，对个人健康的影响可能很严重，并可能反映出环境条件的恶化。一只成年雄性自由放养的布兰丁龟 ( Emydoidea blandingii ) 最初于 2005 年被捕获并被认为是健康的，于 2018 年以 1 × 1.5 厘米的口内宽基右下颌肿块被重新捕获。进行了切除活检，组织病理学显示为鳞状细胞癌 (SCC)。共识疱疹病毒 PCR 在肿瘤内鉴定出一种新型疱疹病毒（建议命名为Emydoidea herpesvirus 2 [EBHV-2]）。EBHV-2 与Terrapene具有 85% 的序列同源性疱疹病毒 2 (TerHV-2)，一种与东部箱龟 ( Terrapene carolina carolina ) 中的纤维乳头状瘤相关的疱疹病毒。已经在多种海龟物种中发现了与病毒相关的纤维乳头状瘤，并对它们的种群产生了衰弱的影响，但迄今为止，很少报道与病毒相关的 SCC。