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Copper-promoted cyanation of aryl iodides with N,N-dimethyl aminomalononitrile
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2021-01-22 , DOI: 10.1016/j.tetlet.2020.152749 Si-Zhan Liu , Jing Li , Cao-Gen Xue , Xue-Tao Xu , Lin-Sheng Lei , Chen-Yu Huo , Zhen Wang , Shao-Hua Wang
中文翻译:
N,N-二甲基氨基丙二腈经铜促进的芳基碘化物的氰化
更新日期:2021-02-04
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2021-01-22 , DOI: 10.1016/j.tetlet.2020.152749 Si-Zhan Liu , Jing Li , Cao-Gen Xue , Xue-Tao Xu , Lin-Sheng Lei , Chen-Yu Huo , Zhen Wang , Shao-Hua Wang
A copper-promoted cyanation of aryl iodides has been successfully developed by using N,N-dimethyl aminomalononitrile as the cyanide source with moderate toxicity and better stability. This reaction features broad substrate scope, excellent reaction yields, readily available catalyst, and simple reaction conditions.
中文翻译:
N,N-二甲基氨基丙二腈经铜促进的芳基碘化物的氰化
以N,N-二甲基氨基丙二腈为氰化物源,具有中等毒性和较好的稳定性,已成功开发出铜促进的芳基碘氰化反应。该反应具有广泛的底物范围,优异的反应产率,容易获得的催化剂和简单的反应条件。